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SOURCE:   Almanac of Modern Science and Education. Tambov: Gramota, 2014. № 7. P. 106-112. ISSN 1993-5552.
SCIENTIFIC AREA: Medical Sciences
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FIBRIN-MONOMERS SOLUBLE COMPLEXES AS MARKERS OF EARLY DIAGNOSTICS OF ACUTE THROMBOTIC INJURY

Petukhova Elena Valer'evna, Shmakova Irina Viktorovna, Dolgopolova Irina Evgen'evna, Vasil'eva Elena Grigor'evna, Bulgakova Yuliya Vladimirovna, Osina Ol'ga Vladimirovna, Beskrovnova Tat'yana Aleksandrovna, Trubeko Ol'ga 
Federal State Budgetary Institution "The United Hospital and Polyclinic" of the Department for Presidential Affairs of the Russian Federation in Moscow


Abstract. The article examines the interconnection of acute thrombotic injury and significant increase in the amount of fibrin-monomers soluble complexes in blood. The authors give the description of clinical cases, where the identification of significant increase in the amount of fibrin-monomers soluble complexes during the first hours of disease development in the conditions of the absence of any diagnostically significant changes of other markers is shown. The authors conclude that the identification of fibrin-monomers soluble complexes can be used in laboratory diagnostics as an early marker of acute thrombotic injury development.
Key words and phrases: острое тромботическое поражение, маркёр, растворимые комплексы фибрин-мономеров, Д-димеры, фибриноген, антикоагулянтная терапия, acute thrombotic injury, marker, fibrin-monomers soluble complexes, D-dimers, fibrinogen, anticoagulant therapy.
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