GRAMOTA Publishers suggests publishing your scientific articles in periodicals
Pedagogy. Theory & PracticePhilology. Theory & PracticeManuscript

Archive of Scientific Articles

SOURCE:   Almanac of Modern Science and Education. Tambov: Gramota, 2013. 10. P. 103-106.
SCIENTIFIC AREA: Medical Sciences
To Publish Article in the Journal | To show issue content | To show all articles in section | Subject Index

License Agreement on scientific materials use.

VITAMINS E AND C INFLUENCE ON INDEXES OF OXIDATIVE STATUS OF RATS KIDNEY TISSUE AND BLOOD HAVING STREPTOZOTOCIN DIABETES

Krasnyi Mikhail Romanovich, Sergienko Viktoriya Aleksandrovna, Sergienko Aleksandr Alekseevich
Danylo Halytsky Lviv National Medical University, Ukraine


Abstract. The article is aimed at researching the peculiarities of vitamins and influence on some indexes of the oxidative status of rats kidney tissue and blood having streptozotocin diabetes. It is ascertained that vitamins and use was accompanied with the significant reduction of the level of the primary and final products of lipids peroxide oxidation, the normalization of the concentration of deoxidated proteins SH-groups and catalase activation in rats kidney tissue. The results of our research indicate that it is reasonable to use antioxidant vitamins and for the normalization of general antioxidant status and some its components.
Key words and phrases: , , , , , streptozotocin diabetes, kidneys, antioxidant status, lipids peroxide oxidation, vitamins and .
Open the whole article in PDF format. Free PDF-files viewer can be downloaded here.

 

References:
  1. Arutyunyan A. V., Dubinina E. E., Zybina N. N. Metody otsenki svobodnoradikal'nogo okisleniya i antioksidantnoi sistemy organizma: metodicheskie rekomendatsii. SPb., 2000. 104 s.
  2. Korolyuk M. A., Ivanova L. I., Maiorova I. G. Metody opredeleniya aktivnosti katalazy // Laboratornoe delo. 1988. 1. C. 16-19.
  3. Lapach S. N., Chubenko A. V., Babich P. N. Statisticheskie metody v mediko-biologicheskikh issledovaniyakh s ispol'zovaniem Excel. K.: Morion, 2000. 320 s.
  4. Rukovodstvo po izucheniyu biologicheskogo okisleniya polyarograficheskim metodom / pod red. G. M. Franka. M., 1973. 378 c.
  5. Blumenthal S. S. Evolution of Treatment for Diabetic Nephropathy: Historical Progression from RAAS Inhibition and Onward // Postgraduate Medicine. 2011. 2. R. 166-179.
  6. Endemann D. H., Schiffrin E. L. Nitric Oxide, Oxidative Excess, and Vascular Complications of Diabetes Mellitus // Current Hypertension Reports. 2004. 2. P. 85-89.
  7. Gray S. P., Cooper M. E. Alleviating the Burden of Diabetic Nephropathy // Nature Reviews Nephrology. 2011. 1. P. 71-73.
  8. Haidara M. A., Yassin H. Z., Rateb M. Role of Oxidative Stress in Development of Cardiovascular Complications in Diabetes Mellitus // Current Vascular Pharmacology. 2006. 3. P. 215-227.
  9. Hayden M. R., Tyagi S. C. Is Type 2 Diabetes Mellitus a Vascular Disease (Atheroscleropathy) with Hyperglycemia Late Manifestation? The Role of NOS, NO, and Redox Stress // Cardiovascular Diabetology. 2003. 2. P. 1-10.
  10. Kanwar Y. S., Sun L., Xie P. A Glimpse of Various Pathogenetic Mechanisms of Diabetic Nephropathy // The Annual Review of Pathology: Mechanisms of Disease. 2011. 2. P. 395-423.
  11. Nishikawa T., Edelstein D., Brownlee M. The Missing Link: a Single Unifying Mechanism for Diabetic Complications // Kidney International. 2000. 1 (Special Issue). P. 26-30.
  12. Thomas M. C., Groop P. H., Tryggvason K. Towards Understanding the Inherited Susceptibility for Nephropathy in Diabetes // Current Opinion Nephrology Hypertension. 2012. 2. R. 195-202.

To Publish Article in the Journal | To show issue content | To show all articles in section | Subject Index

2006-2020 GRAMOTA Publishers

site development and search engine optimization (seo): krav.ru