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SOURCE:    Almanac of Modern Science and Education. Tambov: Gramota, 2013. № 10. P. 103-106.
SCIENTIFIC AREA:    Medical Sciences
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Krasnyi Mikhail Romanovich, Sergienko Viktoriya Aleksandrovna, Sergienko Aleksandr Alekseevich
Danylo Halytsky Lviv National Medical University, Ukraine

Abstract. The article is aimed at researching the peculiarities of vitamins Е and С influence on some indexes of the oxidative status of rats’ kidney tissue and blood having streptozotocin diabetes. It is ascertained that vitamins Е and С use was accompanied with the significant reduction of the level of the primary and final products of lipids peroxide oxidation, the normalization of the concentration of deoxidated proteins SH-groups and catalase activation in rats’ kidney tissue. The results of our research indicate that it is reasonable to use antioxidant vitamins Е and С for the normalization of general antioxidant status and some its components.
Key words and phrases: стрептозотоциновый диабет, почки, антиоксидантный статус, перекисное окисление липидов, витамины Е и С, streptozotocin diabetes, kidneys, antioxidant status, lipids peroxide oxidation, vitamins Е and С
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  1. Arutyunyan A. V., Dubinina E. E., Zybina N. N. Metody otsenki svobodnoradikal'nogo okisleniya i antioksidantnoi sistemy organizma: metodicheskie rekomendatsii. SPb., 2000. 104 s.
  2. Korolyuk M. A., Ivanova L. I., Maiorova I. G. Metody opredeleniya aktivnosti katalazy // Laboratornoe delo. 1988. № 1. C. 16-19.
  3. Lapach S. N., Chubenko A. V., Babich P. N. Statisticheskie metody v mediko-biologicheskikh issledovaniyakh s ispol'zovaniem Excel. K.: Morion, 2000. 320 s.
  4. Rukovodstvo po izucheniyu biologicheskogo okisleniya polyarograficheskim metodom / pod red. G. M. Franka. M., 1973. 378 c.
  5. Blumenthal S. S. Evolution of Treatment for Diabetic Nephropathy: Historical Progression from RAAS Inhibition and Onward // Postgraduate Medicine. 2011. № 2. R. 166-179.
  6. Endemann D. H., Schiffrin E. L. Nitric Oxide, Oxidative Excess, and Vascular Complications of Diabetes Mellitus // Current Hypertension Reports. 2004. № 2. P. 85-89.
  7. Gray S. P., Cooper M. E. Alleviating the Burden of Diabetic Nephropathy // Nature Reviews Nephrology. 2011. № 1. P. 71-73.
  8. Haidara M. A., Yassin H. Z., Rateb M. Role of Oxidative Stress in Development of Cardiovascular Complications in Diabetes Mellitus // Current Vascular Pharmacology. 2006. № 3. P. 215-227.
  9. Hayden M. R., Tyagi S. C. Is Type 2 Diabetes Mellitus a Vascular Disease (Atheroscleropathy) with Hyperglycemia Late Manifestation? The Role of NOS, NO, and Redox Stress // Cardiovascular Diabetology. 2003. № 2. P. 1-10.
  10. Kanwar Y. S., Sun L., Xie P. A Glimpse of Various Pathogenetic Mechanisms of Diabetic Nephropathy // The Annual Review of Pathology: Mechanisms of Disease. 2011. № 2. P. 395-423.
  11. Nishikawa T., Edelstein D., Brownlee M. The Missing Link: a Single Unifying Mechanism for Diabetic Complications // Kidney International. 2000. № 1 (Special Issue). P. 26-30.
  12. Thomas M. C., Groop P. H., Tryggvason K. Towards Understanding the Inherited Susceptibility for Nephropathy in Diabetes // Current Opinion Nephrology Hypertension. 2012. № 2. R. 195-202.

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