GRAMOTA Publishers suggests publishing your scientific articles in periodicals
Pedagogy. Theory & PracticePhilology. Theory & PracticeManuscript

Archive of Scientific Articles

SOURCE:   Almanac of Modern Science and Education. Tambov: Gramota, 2014. № 9. P. 42-45.
SCIENTIFIC AREA: Medical Sciences
To Publish Article in the Journal | To show issue content | To show all articles in section | Subject Index

License Agreement on scientific materials use.

ROLE OF PROTEOLYTIC ENZYMES ACTIVITY IN DEVELOPING DELAY OF EMBRYO GROWTH SECONDARY TO CHRONIC PLACENTAL INSUFFICIENCY

GULAYA Valeriya Sergeevna
Siberian State Medical University


Abstract. The article highlights new approaches to the early diagnosis of chronic placental insufficiency, which more often than other predisposing factors serves as a backdrop for the development of embryo growth delay. The proteolytic enzymes - trypsin- and elastosis-like proteinases - are promising ones in the role of biochemical markers that allow predicting the development of this disease at the early stages of gestation. Proteolytic activity in the body, in its turn, is regulated by inhibitory systems, in particular by ? 1-proteinase inhibitor. Many metabolic processes depend on the relation of proteolysis system activity and the activity of the inhibitory system of the body, namely the refractoriness of vessels to vasoconstrictors and the formation of compensatory-adaptive mechanisms at tissue level in the "mother - placenta - embryo" system.
Key words and phrases: трипсиноподобные протеиназы, эластазоподобные протеиназы, ? 1-протеиназный ингибитор, задержка роста плода, хроническая плацентарная недостаточность, trypsin-like proteinases, elastosis-like proteinases, ? 1-proteinase inhibitor, delay of embryo growth, chronic placental insufficiency.
Open the whole article in PDF format. Free PDF-files viewer can be downloaded here.

 

References:
  1. Ailamazyan E. K. Akusherstvo: natsional'noe rukovodstvo / pod red. E. K. Ailamazyana, V. I. Kulakova, V. E. Radzinskogo, G. M. Savel'evoi. M., 2009. 1200 s.
  2. Garmasheva N. L., Konstantinova N. N. Patofiziologicheskie osnovy okhrany vnutriutrobnogo razvitiya cheloveka. L., 1985. 159 s.
  3. Dobrokhotova Yu. E., Milovanov A. P., Dzhobava E. M., Dzeigova E. A. Platsentarnaya nedostatochnost' u beremennykh s khronicheskoi venoznoi nedostatochnost'yu: nekotorye aspekty etiologii, patogeneza i diagnostiki // Mat' i ditya: materialy VII vseross. nauchn. foruma. M., 2006. S. 11-14.
  4. Mamedalieva N. M., Sidel'nikova V. M. Znachenie opredeleniya trofoblasticheskogo-1-glikoproteida dlya rannei diagnostiki i prognozirovaniya platsentarnoi nedostatochnosti u beremennykh s privychnym nevynashivaniem // Akusherstvo i ginekologiya. 1991. № 11. S. 22-24.
  5. Sidorova I. S., Kulakova V. I., Makarova I. O. Rukovodstvo po akusherstvu i ginekologii. M.: Meditsina, 2006.
  6. Creasy and Resnik’s Maternal-Fetal Medicine: Principles and Practice. Sixth edition. Philadelphia, 2009.
  7. Sato B., Katagiri Y. U., Miyado K. Lipid Rafts Enriched in MonosialylGb5Cer Carrying the Stage-Specific Embryonic Antigen-4 Epitope Are Involved in Development of Mouse Preimplantation Embryos at Cleavage Stage // BMC Developmental Biology. 2011. Vol. 14. P. 11-22.

To Publish Article in the Journal | To show issue content | To show all articles in section | Subject Index

© 2006-2020 GRAMOTA Publishers

site development and search engine optimization (seo): krav.ru